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Anti -BCAS3 (Breast Carcinoma Amplified Sequence 3, FLJ20128, GAOB1, MAAB, MGC4973)
Anti -BCAS3 (Breast Carcinoma Amplified Sequence 3, FLJ20128, GAOB1, MAAB, MGC4973)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| BCAS3 acts as an ERá coactivator in breast cancer cells. It has been demonstrated that PELP1, a newly described ERá coregulator, is recruited to BCAS3 chromatin and activates its expression. Analysis of the BCAS3 sequence for functional motifs and evidence from biochemical fractionation suggested that BCAS3 acts as a transcriptional coactivator. Results from chromatin immunoprecipitation, reporter assays, and expression studies further validated the coactivator function of BCAS3 for ERá. BCAS3 physically associated with histone H3 and histone acetyltransferase complex protein P/CAF and possessed histone acetyltransferase activity. | | | Catalog # | B0395-60A | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.2mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized maps to a region between residue 870 and the C-terminus (residue 928) of human Breast Carcinoma Amplified Sequence 3 using the numbering given in entry BAB15156.1 (GeneID 54828). | | Specificity | This antibody is specific to the human BCAS3 protein. Species Crossreactivity: Human. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | BCAS-3 |
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