Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to B Cells » Anti -BLNK (B cell Linker, BASH, Bca, B-cell Adapter Containing a SH2 Domain Protein, B-cell Adapter Containing a Src Homology 2 Domain Protein, Cytoplasmic Adapter Protein, Lymphocyte Antigen 57, Ly57, Ly-57, Lyw-57, Src Homology 2 Domain-containing Leukocyte

Anti -BLNK (B cell Linker, BASH, Bca, B-cell Adapter Containing a SH2 Domain Protein,
B-cell Adapter Containing a Src Homology 2 Domain Protein, Cytoplasmic Adapter Protein,
Lymphocyte Antigen 57, Ly57, Ly-57, Lyw-57, Src Homology 2 Domain-containing Leukocyte

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B
BLNK (B cell linker protein) is an adaptor molecule that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). This activation leads to an increase in the tyrosine phosphorylation of a number of proteins due to activation of nonreceptor protein tyrosine kinases (PTK) including Syk, which is responsible for the tyrosine phosphorylation of BLNK. BLNK is cytosolic protein identified as two phosphoproteins migrating at 68 and 70kD in SDS/PAGE (alternatively spliced forms of human BLNK). Mapping of the tyrosine residues in BLNK reveal three tyrosines that bind PLC-gamma2, and two tyrosines that bind the Tec family kinase Btk, the Vav nucleotide exchange factor and the adaptor Nck.
Catalog #B0397-01M
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
PurityPurified
ImmunogenFusion protein corresponding to aa71-356 of human BLNK.
SpecificityRecognizes mouse BLNK.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesB-cell Linker Protein


External Links