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Anti -BLNK, ID (B-cell Linker Protein, Cytoplasmic Adapter Protein, B-cell Adapter Containing a SH2 Domain Protein, B-cell Adapter Containing a Src Homology 2 Domain Protein, Src Homology 2 Domain-containing Leukocyte Protein of 65kD, SLP-65, SLP65, BASH, BLNK)
Anti -BLNK, ID (B-cell Linker Protein, Cytoplasmic Adapter Protein, B-cell Adapter
Containing a SH2 Domain Protein, B-cell Adapter Containing a Src Homology 2 Domain
Protein, Src Homology 2 Domain-containing Leukocyte Protein of 65kD, SLP-65, SLP65, BASH,
BLNK)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| BLNK is a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in its gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. | | | Catalog # | B0397-15A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide selected from the Center region of human BLNK (KLH). | | Specificity | Recognizes human BLNK. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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