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You are here:Home » Molecular Biology » Growth Factors-BCMA » B Cell Maturation Protein (BCMA), Recombinant, Human

B Cell Maturation Protein (BCMA), Recombinant, Human

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Specifications

BCMA is a member of the TNF receptor superfamily. It binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines. It plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184aa type I transmembrane protein, which contains a 54aa extracellular domain, a 23aa transmembrane domain, and a 107aa extracellular domain. Recombinant soluble BCMA is a 50aa polypeptide (5.3kD) comprising the TNFR homologous region of the BCMA protein.
Catalog #B0410
Recombinant protein corresponding to human B Cell Maturation Protein expressed in E. coli.
Amino Acid Sequence AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O, 0.1% BSA or HSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Country of OriginUSA
CAS NumberN/A
Molecular Weight5.3kD
SourceE. coli
Purity95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug)
FormSupplied as a lyophilized powder without additives. Reconstitute in sterile ddH2O, 0.1% BSA or HSA to 0.1-1mg/ml. Do not vortex.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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