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B Cell Maturation Protein (BCMA), Recombinant, Human
B Cell Maturation Protein (BCMA), Recombinant, Human
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| BCMA is a member of the TNF receptor superfamily. It binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines. It plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184aa type I transmembrane protein, which contains a 54aa extracellular domain, a 23aa transmembrane domain, and a 107aa extracellular domain. Recombinant soluble BCMA is a 50aa polypeptide (5.3kD) comprising the TNFR homologous region of the BCMA protein. | | | Catalog # | B0410 | | Recombinant protein corresponding to human B Cell Maturation Protein expressed in E. coli | | AA Sequence | AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O, 0.1% BSA or HSA. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Country of Origin | USA | | Molecular Weight | 5.3kD | | Source | Human, recombinant expressed in E. coli | | Purity | 95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug) | | Form | Supplied as a lyophilized powder without additives. Reconstitute in sterile ddH2O, 0.1% BSA or HSA to 0.1-1mg/ml. Do not vortex. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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