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Specifications

Clone Host Grade Applications Polyclonal Rabbit Affinity Purified E B

Bcl-2 is a protein localized on the mitochondrial outer membrane, endoplasmic reticulum, and nuclear envelope. It supresses apoptosis modulated by homodimerization or association with Bax and Bad, two cell death promoters. It may contribute to tumorigenesis by prolonging cell survival and by mutations in the Bcl-2 gene.
Catalog #	B0807-06B
Applications	Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Polyclonal
Host	Rabbit
Source	Human
Concentration	As reported
Form	Supplied as a liquid in PBS, pH 7.2.
Purity	Purified by Protein G affinity chromatography.
Immunogen	Synthetic peptide (GAAPAPGIFSSQPG) corresponding to aa41-54 of human Bcl-2
Specificity	Recognizes human B-cell Leukaemia/lymphoma 2
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.