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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -Bcl 6, CT (B Cell Leukemia 6, Lymphoma 6, Zinc finger protein 51, LAZ3)
Anti -Bcl 6, CT (B Cell Leukemia 6, Lymphoma 6, Zinc finger protein 51, LAZ3)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IP IH IC |
|
| Bcl-6 (also known as LAZ3) is a member of the POZ/zinc finger (POK) family that contains an N-terminal POZ domain and 6 C-terminal zinc finger motifs (1). Bcl-6 is a transcriptional regulator that plays an important role in lymphocyte, myocyte, male germ cells, and keratinocyte survival and or differentiation (2-3). Bcl-6 has also been found to repress a number of genes involved in B cell activation and terminal differentiation, inflammation and cell cycle regulation (4). Chromosomal aberration in Bcl-6 may be a cause of B-cell non –Hodgkin lymphoma and B-cell leukemia (5). | | | Catalog # | B0807-11F | | Applications | Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-2000 | | Immunohistochemistry:1:50-1:100 | | Immunocytochemistry: 1:100-1:250 | | Immunoprecipitation: 1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 6k40 | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide and 0.05% BSA. | | Purity | Supernatant | | Immunogen | A synthetic peptide corresponding to residues in the C-terminus of human Bcl-6. | | Specificity | Recognizes human Bcl-6. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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