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BCMA, Control Peptide (B Cell Maturation Protein)
BCMA, Control Peptide (B Cell Maturation Protein)
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| Synthetic peptide mapping at the C-terminus of human BCMA (8). | | | Catalog # | B0807-50A | | Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL- 2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified (6,7). BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. | | Applications | Suitable for use in ELISA, Western Blotting. Other applications not tested. | | Recommended Dilution | Western Blotting: 2-5ug/ml | | Optimal dilutions to be determined by the researcher. | | Corresponding Antibody | BAFF Receptor B0807-50A | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Purity | Purified | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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