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You are here:Home » Molecular Biology » MB-Apoptosis » BCMA, Control Peptide (B Cell Maturation Protein)

BCMA, Control Peptide (B Cell Maturation Protein)

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Specifications

Synthetic peptide mapping at 16 aa near the C-terminus of human BCMA.
Catalog #B0807-50A
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL- 2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified (6,7). BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
ApplicationsSuitable for use in Antibody Blocking. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Corresponding AntibodyBAFF Receptor B0807-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PurityPurified
Concentration~0.2mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% BSA, 0.02% sodium azide.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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