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You are here:Home » Molecular Biology » Growth Factors-Defensin » BD4, Recombinant, Human (beta Defensin-4)

BD4, Recombinant, Human (beta Defensin-4)

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Specifications

Defensin beta 4 (BD-4) is a secreted cationic antimicrobial peptide and member of the beta-defensin family, highly expressed in the testis, which plays an important role in innate immunity. Studies have shown that the expression of BD-4 is up-regulated in respiratory epithelial cells, following infection by both gram-positive and gram-negative bacteria, and that BD-4 acts in synergy with lysozyme and BD-3.
Catalog #B0903-26
SourceE.coli
ApplicationsSuitable for use in Functional Assays. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Endotoxin 1EU/ug
Molecular Weight 6.0kD (50 amino acid residues)
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 0.1-100ng/ml.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity98% (SDS PAGE and HPLC).
Concentration~0.1mg/ml
FormSupplied as a lyophilized powder. Reconstitute with 200ul dH20.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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