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BD4, Recombinant, Human (beta Defensin-4)
BD4, Recombinant, Human (beta Defensin-4)
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| Defensin beta 4 (BD-4) is a secreted cationic antimicrobial peptide and member of the beta-defensin family, highly expressed in the testis, which plays an important role in innate immunity. Studies have shown that the expression of BD-4 is up-regulated in respiratory epithelial cells, following infection by both gram-positive and gram-negative bacteria, and that BD-4 acts in synergy with lysozyme and BD-3. | | | Catalog # | B0903-26 | | Source | E.coli | | Applications | Suitable for use in Functional Assays. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Endotoxin | 1EU/ug | | Molecular Weight | 6.0kD (50 amino acid residues) | | Biological Activity | Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-100ng/ml. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Source | E. coli | | Purity | 98% (SDS PAGE and HPLC). | | Concentration | ~0.1mg/ml | | Form | Supplied as a lyophilized powder. Reconstitute with 200ul dH20. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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