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Berninamycin A (Berninamycin, Antibiotic U27810)
Berninamycin A (Berninamycin, Antibiotic U27810)
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| Berninamycin A is an antibiotic discovered in 1976 from a strain of Streptomyces. Berninamycin A is a macrocyclic "peptide" comprising atypical amino acids linked to thiazole and oxazoles. Chemically very complex, berninamycin A is an inducer of tipA, a gene that controls the bacterial transcription regulators, TipAL and TipAS, members of the MerR proteins that are central regulators in multidrug resistence. Closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1. | | | Catalog # | B1078-75 | | DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water | | CAS Number | 58798-97-3 | | Molecular Formula | C51H51N15O15S | | Molecular Weight | 1146.1210000000000946 | | Source | Streptomyces sp. | | Purity | >99% | | Form | White solid | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Berninamycin, Antibiotic U27810 |
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