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You are here:Home » Biochemicals » Biochem-Antibiotics » Berninamycin A (Berninamycin, Antibiotic U27810)

Berninamycin A (Berninamycin, Antibiotic U27810)


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Berninamycin A is an antibiotic discovered in 1976 from a strain of Streptomyces. Berninamycin A is a macrocyclic "peptide" comprising atypical amino acids linked to thiazole and oxazoles. Chemically very complex, berninamycin A is an inducer of tipA, a gene that controls the bacterial transcription regulators, TipAL and TipAS, members of the MerR proteins that are central regulators in multidrug resistence. Closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.
Catalog #B1078-75
DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water
CAS Number58798-97-3
Molecular FormulaC51H51N15O15S
Molecular Weight1146.1210000000000946
SourceStreptomyces sp.
FormWhite solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesBerninamycin, Antibiotic U27810

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