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Bexarotene, Free Acid (Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069, SR-11247)
Bexarotene, Free Acid (Targretin, Targretyn, Targrexin, LGD-1069, LG 1069, LG100069,
SR-11247)
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| Bexarotene (LGD-1069) is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas (CTCL). | | | Catalog # | B1085-32C | | Solubility | Soluble in DMSO at 65mg/ml. Soluble in ethanol at 10mg/ml with warming; very poorly soluble in water. Maximum solubility in plain water is estimated to be about 10-50uM. | | Storage and Stability | May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. | | CAS Number | 153559-49-0 | | Molecular Formula | C24H28O2 | | Molecular Weight | 348.48 | | Purity | ~99% | | Form | Supplied as a white powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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