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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -Biglycan (BGN, Bone/Cartilage Proteoglycan I, DSPG1, PG-S1, SLRR1A)

Anti -Biglycan (BGN, Bone/Cartilage Proteoglycan I, DSPG1, PG-S1, SLRR1A)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival. This gene is a candidate gene for the Happle syndrome.
Catalog #B1089-40A
Positive Control Rat Skin lysate
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:8000.
Western Blot: 0.1-0.3ug/ml. ~ 38-40kD band observed in Rat Skin lysates (calculated MW of 41.7kD according to rat NP_058783.1 and human NP_001702.1 ).
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, C-DRLAIQFGNYKK, representing the C Terminus of the human protein according to NP_001702.1. Homology
SpecificitySpecies Crossreactivity: Rat. Other species not tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPGI, Dermatan Sulfate Proteoglycan I, Small Leucine-rich Protein 1A


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