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You are here:Home » Molecular Biology » MB-Enzymes, Reductase » Biliverdin IX beta Reductase,1-206aa, Recombinant, Human (BLVRB)

Biliverdin IX beta Reductase,1-206aa, Recombinant, Human (BLVRB)

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Specifications

Biliverdin reductase B (BLVRB) is an enzyme (EC 1.3.1.24) that converts biliverdin to bilirubin, converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRB is found that major erythrocytic heme catabolic pathway in humans and most mammalian species. Biliverdin reductase is abundantly expressed in kidney, spleen, liver and brain as well as at lower levels in the thymus and minimal levels being detected in testis.
Catalog #B1150-03
Sequence of amino acidsMAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG
ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD
LGHFMLRCLT TDEYDGHSTY PSHQYQ
Molecular Weight 22.1kD (206aa)
Endotoxin 1.0 EU/ug of protein (determined by LAL method)
Storage and StabilityFor long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight22.1kD
SourceE. coli
Purity95% by SDS PAGE. Recombinant human BLVRB protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris pH 8.5, 10% glycerol, 1mM DTT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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