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You are here:Home » Biochemicals » Biochem-Inhibitors » BIO (2Z, 3E)-6-Bromo-3-(hydroxyimino)-[2,3-biindolinylidene]-2-one

BIO (2Z, 3E)-6-Bromo-3-(hydroxyimino)-[2,3-biindolinylidene]-2-one


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A potent, selective, reversible and ATP-competitive inhibitor of GSK-3 / (IC50 = 5nM). Under a feeder-free condition, BIO maintains embryonic stem cells (hESCs) in the undifferented state.
Catalog #B1549
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO or ethanol. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Protect from air. Light sensitive.
CAS Number667463-62-9
Molecular FormulaC16H10BrN3O2
Molecular Weight356.17
FormSupplied as a crystalline solid. Reconstitute in 10mg/ml DMSO or 0.5mg/ml Ethanol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names(2Z,3E)-6?-Bromo-3-(hydroxyimino)-[2,3?-biindolinylidene]-2?-one

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