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You are here:Home » Molecular Biology » MB-Binding Proteins » BIP, aa20-650, His-Tag, Recombinant, Human (Binding immunoglobulin Protein, HSPA5, Heat Shock 70kD protein 5, GRP78, Glucose-regulated protein, 78kD, MIF2)

BIP, aa20-650, His-Tag, Recombinant, Human (Binding immunoglobulin Protein, HSPA5, Heat
Shock 70kD protein 5, GRP78, Glucose-regulated protein, 78kD, MIF2)

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Specifications

Binding immunoglobulin protein (BiP) belongs to the family of ~70 kD heat shock proteins (HSP 70). It is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis.
Catalog #B1770-01
Molecular Weight 71kD
Sequence of amino acidsMEEDKKEDVG TVVGIDLGTT YSCVGVFKNG RVEIIANDQG NRITPSYVAF TPEGERLIGD AAKNQLTSNP ENTVFDAKRL IGRTWNDPSV QQDIKFLPFK VVEKKTKPYI QVDIGGGQTK TFAPEEISAM VLTKMKETAE AYLGKKVTHA VVTVPAYFND AQRQATKDAG TIAGLNVMRI INEPTAAAIA YGLDKREGEK NILVFDLGGG TFDVSLLTID NGVFEVVATN GDTHLGGEDF DQRVMEHFIK LYKKKTGKDV RKDNRAVQKL RREVEKAKRA LSSQHQARIE IESFYEGEDF SETLTRAKFE ELNMDLFRST MKPVQKVLED SDLKKSDIDE IVLVGGSTRI PKIQQLVKEF FNGKEPSRGI NPDEAVAYGA AVQAGVLSGD QDTGDLVLLD VCPLTLGIET VGGVMTKLIP RNTVVPTKKS QIFSTASDNQ PTVTIKVYEG ERPLTKDNHL LGTFDLTGIP PAPRGVPQIE VTFEIDVNGI LRVTAEDKGT GNKNKITITN DQNRLTPEEI ERMVNDAEKF AEEDKKLKER IDTRNELESY AYSLKNQIGD KEKLGGKLSS EDKETMEKAV EEKIEWLESH QDADIEDFKA KKKELEEIVQ PIISKLYGSA GPPPTGEEDT AELEHHHHHH
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight71kD
SourceE. coli
Purity90% by SDS PAGE . Recombinant human BIP protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration~1mg/ml
FormSupplied as a liquid in 20mM Tris pH 8.0, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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