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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -BIRC3, CT (Baculoviral IAP Repeat-containing Protein 3, Apoptosis Inhibitor 2, API2, C-IAP2, IAP Homolog C, Inhibitor of Apoptosis Protein 1, IAP-1, hIAP-1, hIAP1, RING Finger Protein 49, TNFR2-TRAF-signaling Complex Protein 1, API2, IAP1, MIHC, RNF49)

Anti -BIRC3, CT (Baculoviral IAP Repeat-containing Protein 3, Apoptosis Inhibitor 2, API2,
C-IAP2, IAP Homolog C, Inhibitor of Apoptosis Protein 1, IAP-1, hIAP-1, hIAP1, RING Finger
Protein 49, TNFR2-TRAF-signaling Complex Protein 1, API2, IAP1, MIHC, RNF49)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Apoptosis inhibitor 2 (API2) is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. API2 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The aa sequence predicts three baculovirus IAP repeat domains and a ring finger domain. The names of API1 and API2 have been confusing. Suffice it to say that 'apoptosis inhibitor 2' is hiap-1 (inhibitor of apoptosis 1).
Catalog #B2050-01M
ApplicationsSuitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to CRSTIKGTVRT of human BIRC3 at C-terminal.
SpecificityRecognizes human BIRC3. Species sequence homology: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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