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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -BIRC3 (Baculoviral IAP Repeat-containing Protein 3, Apoptosis Inhibitor 2, API2, IAP-1, hIAP-1, hIAP1, RING Finger Protein 49, TNFR2-TRAF-signaling Complex Protein 1, C-IAP2, IAP Homolog C, Inhibitor of Apoptosis Protein 1, API2, IAP1, MIHC, RNF49)

Anti -BIRC3 (Baculoviral IAP Repeat-containing Protein 3, Apoptosis Inhibitor 2, API2,
IAP-1, hIAP-1, hIAP1, RING Finger Protein 49, TNFR2-TRAF-signaling Complex Protein 1,
C-IAP2, IAP Homolog C, Inhibitor of Apoptosis Protein 1, API2, IAP1, MIHC, RNF49)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
CIAP-2 is a member of the inhibitor of apoptosis family of proteins that inhibit the proteolytic activity of mature caspases. Human cIAP-2 is a 604aa protein that contains 3 BIR domains, a RING finger domain, and a caspase recruitment domain (CARD). cIAP-2 inhibits caspases through the direct interaction of its BIR domain with the active caspase. Caspase activity may be restored through interactions with the Reaper like motif on mitochondrial proteins such as SMAC/Diablo or HtrA2/Omi. cIAP-2 is reported to be cleaved by HtrA2/Omi.
Catalog #B2050-01N
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5mg/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 8-25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No12K15
HostMouse
SourceHuman
Concentration~0.5mg/ml after reconstitution
FormSupplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant corresponding to aa2-604 from human BIRC3 expressed in E. coli.
SpecificityRecognizes human BIRC3. Species Crossreactivity: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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