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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -Blimp-1 (BLIMP 1, BLIMP1, B Lymphocyte Induced Maturation Protein 1, Positive Regulatory Domain I Binding Factor 1, PR Domain Containing 1, PRDI BF1, PRDM1)
Anti -Blimp-1 (BLIMP 1, BLIMP1, B Lymphocyte Induced Maturation Protein 1, Positive
Regulatory Domain I Binding Factor 1, PR Domain Containing 1, PRDI BF1, PRDM1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IC |
|
| Human BLIMP1(B lymphocyteinduced maturation protein 1, also known as PRDM1)is a 91kD zincfinger transcriptional repressor that promotes B cell maturation into plasma cells. It is 789aa in length, and contains an Nterminal SET domain (aa64170) and our Cterminal C2H2t ype zincfinger motifs (aa 539645). The SET domain interacts with chromatin modifers, while the zinc fingers bind to DNA. There is one 80kD 691aa alternate splice form that utilizes an | | | intenal start site. This results in a substitution of three aa for the first 101aa of the long form, and the loss of the SET domain. At least 10 mutations exist, resulting in proteins of 61603aa in length. Over aa667789, human BLIMP1 is 89% aa identical to mouse BLIMP1. | | | Catalog # | B2106-70C | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1mg/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 11D96 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS. | | Purity | Purified by Protein A/G affinity chromatography. | | Immunogen | Recombinant protein corresponding to aa667-789 from human Blimp-1 expressed in E. coli (O75626). | | Specificity | Recognizes human Blimp-1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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