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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -Blimp-1 (BLIMP 1, BLIMP1, B Lymphocyte Induced Maturation Protein 1, Positive Regulatory Domain I Binding Factor 1, PR Domain Containing 1, PRDI BF1, PRDM1)

Anti -Blimp-1 (BLIMP 1, BLIMP1, B Lymphocyte Induced Maturation Protein 1, Positive
Regulatory Domain I Binding Factor 1, PR Domain Containing 1, PRDI BF1, PRDM1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IC
Human BLIMP1(B lymphocyte­induced maturation protein 1, also known as PRDM1)is a 91kD zinc­finger transcriptional repressor that promotes B cell maturation into plasma cells. It is 789aa in length, and contains an N­terminal S­E­T domain (aa64­170) and our C­terminal C2H2­t ype zinc­finger motifs (aa 539­645). The SET domain interacts with chromatin modifers, while the zinc fingers bind to DNA. There is one 80kD 691aa alternate splice form that utilizes an
intenal start site. This results in a substitution of three aa for the first 101aa of the long form, and the loss of the SET domain. At least 10 mutations exist, resulting in proteins of 61­603aa in length. Over aa667­789, human BLIMP1 is 89% aa identical to mouse BLIMP1.
Catalog #B2106-70C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1mg/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No11D96
HostMouse
SourceHuman
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa667-789 from human Blimp-1 expressed in E. coli (O75626).
SpecificityRecognizes human Blimp-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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