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You are here:Home » Antibodies » Abs to Blood Groups » Anti -Blood Group AB

Anti -Blood Group AB

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IP FC
The ABO system is based on differential gylcosylation of lipid or protein on blood cells. The basic carbohydrate chain extending from the protein or lipid is, eg, Type O: Protein or Lipid - Glucose--N-Acetylglucosamine--Galactose--Fucose. The galactose residue can have an additional sugar residue (in addition to the Fucose) attached to it. If the additional residue is N-Acetylgalactosamine, then the individual is Type A. If the additional residue is Galactose, then the individual is Type B. Type A's and Type B's actually differ because they have different enzymes for glycosylation at the Galactose site. Type A: N-Acetylgalactosamine glycosylation; Type B: Galactose glycosylation. Type AB: individuals with both enzymes. (Type AB individuals have N-Acetylgalactosamine on some galactose sites and Galactose on other galactose sites. Type AB are a mixture of Type A and Type B blood.) Type O individuals do not have the enzymes for glycosylation on the galactose site.
Catalog #B2125-12
ApplicationsSuitabe for blood group typing in direct agglutination tests, slide test, tube test, microplate test, ELISA, Western Blot, Flow Cytometry, and Immunoprecipitation. Other applications have not been tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone No1V017
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.3M sodium chloride, 1.25mM EDTA, 0.1% sodium azide.
PurityPurified by ammonium sulfate precipitation.
SpecificityRecognizes AB human blood antigens. Weak crossreactivity with A1; must be diluted appropriately for automated tests.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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