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You are here:Home » Antibodies » Abs to Blood Groups » Anti -Blood Group B

Anti -Blood Group B

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified
The ABO system is based on differential gylcosylation of lipid or protein on blood cells. The basic carbohydrate chain extending from the protein or lipid is, eg, Type O: Protein or Lipid-Glucose--N-Acetylglucosamine--Galactose--Fucose. The galactose residue can have an additional sugar residue (in addition to the Fucose) attached to it. If the additional residue is N-Acetylgalactosamine, then the individual is Type A. If the additional residue is Galactose, then the individual is Type B. Type A's and Type B's actually differ because they have different enzymes for glycosylation at the Galactose site. Type A: N-Acetylgalactosamine glycosylation; Type B: Galactose glycosylation. Type AB: individuals
with both enzymes. (Type AB individuals have N-Acetylgalactosamine on some galactose sites and Galactose on other galactose sites. Type AB are a mixture of Type A and Type B blood.) Type O individuals do not have the enzymes for glycosylation on the galactose site.
Catalog #B2125-14
Application(s) Testing of blood, blood stains, saliva, and biological fluids by absorption-elution test, inhibition test, immunoenzyme test or direct agglutination test.
Storage and StabilityStored at 4°C. Do not freeze.
Clone TypeMonoclonal
IsotypeIgM
Clone No1V021
HostMouse
SourceHuman
Concentration~1 mg/ml
FormSupplied as a liquid in 0.3M sodium chloride, 1.25mM EDTA, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
SpecificityRecognizes B human antigen of the blood group antigens. Weak agglutination with A1 red blood cells treated with proteolytic enzymes.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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