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Anti -Blood Group Lewis y (FUT3, Lewis Y Blood Group)
Anti -Blood Group Lewis y (FUT3, Lewis Y Blood Group)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
IH |
|
| Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y and precursor type 1 chain antigens. Increased expression of Lewis B has been reported in gastric and pancreatic tumors as well as in colorectal cancer. | | | Catalog # | B2125-28H | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: Paraffin and frozen sections | | Optimal dilutions to be determined by the researcher. | | Hybridoma | X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | A70-C/C8 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, 0.05% sodium azide. | | Purity | Purified | | Immunogen | Live cells of the human colorectal carcinoma cell line Ls174T from a NZB/N Bom mouse. | | Specificity | Recognizes the epitope Fuc-a-1-2Gal-b-1-4(Fuc-a-1-3)GlcNAc-b-1 of the human blood group Lewis Y. Does not cross react with the blood group H type 2 antigens or with Lea, sialyl-Lea, Lex , sialyl-Lex, Leb or Lec. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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