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You are here:Home » Antibodies » Abs to Blood Groups » Anti -Blood Group Lewis y (FUT3, Lewis Y Blood Group)

Anti -Blood Group Lewis y (FUT3, Lewis Y Blood Group)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IH
Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y and precursor type 1 chain antigens. Increased expression of Lewis B has been reported in gastric and pancreatic tumors as well as in colorectal cancer.
Catalog #B2125-28H
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Paraffin and frozen sections
Optimal dilutions to be determined by the researcher.
HybridomaX63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone NoA70-C/C8
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.05% sodium azide.
PurityPurified
ImmunogenLive cells of the human colorectal carcinoma cell line Ls174T from a NZB/N Bom mouse.
SpecificityRecognizes the epitope Fuc-a-1-2Gal-b-1-4(Fuc-a-1-3)GlcNAc-b-1 of the human blood group Lewis Y. Does not cross react with the blood group H type 2 antigens or with Lea, sialyl-Lea, Lex , sialyl-Lex, Leb or Lec.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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