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You are here:Home » Antibodies » Abs to Proteins » Anti -BMAL1 (MOP3, Members of PAS Superfamily, Brain And Muscle ARNT-like 1, JAP3, PAS3, CYCLE)

Anti -BMAL1 (MOP3, Members of PAS Superfamily, Brain And Muscle ARNT-like 1, JAP3, PAS3,
CYCLE)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
MOP3 (BMAL1), a general dimerization partner for a subset of the bHLH-PAS (basic-helix-loop-helix-PER-ARNT-SIM) superfamily of transcription regulators, is involved in circadian rhythm generation. MOP3 interacts with MOP4, CLOCK, hypoxia-inducible factor-1 alpha and -2 alpha. This interaction appears to be distinct from that of the more characterized general partner, ARNT (HIF-1 beta).
Catalog #B2179
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.5-1ug/ml using 1ug/ml
Western Blot: 1-10ug/ml using ECL.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceDrosophila
Concentration~1mg/ml
FormLiquid in PBS, pH 7.4, 0.1% BSA, 0.1% sodium azide
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a 22aa sequence of drosophila BMAL1 (1).
SpecificityRecognizes drosophila BMAL1. The immunogen shows no significant sequence homology with mammalian Clock or Per proteins. Significant homology is seen with mammalian USFs (Upstream Stimulatory Factors 1 and 2) and human and mouse BMAL1 and ARNTs.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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