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Anti -BMAL1 (MOP3, Members of PAS Superfamily, Brain And Muscle ARNT-like 1, JAP3, PAS3, CYCLE)
Anti -BMAL1 (MOP3, Members of PAS Superfamily, Brain And Muscle ARNT-like 1, JAP3, PAS3,
CYCLE)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| MOP3 (BMAL1), a general dimerization partner for a subset of the bHLH-PAS (basic-helix-loop-helix-PER-ARNT-SIM) superfamily of transcription regulators, is involved in circadian rhythm generation. MOP3 interacts with MOP4, CLOCK, hypoxia-inducible factor-1 alpha and -2 alpha. This interaction appears to be distinct from that of the more characterized general partner, ARNT (HIF-1 beta). | | | Catalog # | B2179 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 0.5-1ug/ml using 1ug/ml | | Western Blot: 1-10ug/ml using ECL. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Drosophila | | Concentration | ~1mg/ml | | Form | Liquid in PBS, pH 7.4, 0.1% BSA, 0.1% sodium azide | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to a 22aa sequence of drosophila BMAL1 (1). | | Specificity | Recognizes drosophila BMAL1. The immunogen shows no significant sequence homology with mammalian Clock or Per proteins. Significant homology is seen with mammalian USFs (Upstream Stimulatory Factors 1 and 2) and human and mouse BMAL1 and ARNTs. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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