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You are here:Home » Antibodies » Abs to Proteins » Anti -BMAL1 (MOP3, Members of PAS Superfamily, Brain And Muscle ARNT-like 1, JAP3, PAS3, CYCLE)

Anti -BMAL1 (MOP3, Members of PAS Superfamily, Brain And Muscle ARNT-like 1, JAP3, PAS3,
CYCLE)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
MOP3 (BMAL1), a general dimerization partner for a subset of the bHLH-PAS (basic-helix-loop-helix-PER-ARNT-SIM) superfamily of transcription regulators, is involved in circadian rhythm generation. MOP3 interacts with MOP4, CLOCK, hypoxia-inducible factor-1 alpha and -2 alpha. This interaction appears to be distinct from that of the more characterized general partner, ARNT (HIF-1 beta).
Catalog #B2179
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsELISA: 0.5-1ug/ml using 1ug/ml control peptide/well
Western Blot: 1-10ug/ml using ECL
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceDrosophila
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% BSA, 0.1% sodium azide
PurityPurified by affinity chromatography
ImmunogenSynthetic peptide corresponding to 22aa of Drosophila BMAL1
SpecificityRecognizes Drosophila BMAL1. Significant homology is seen with mammalian USFs (Upstream Stimulatory Factors 1 and 2) and human and mouse BMAL1 and ARNTs. The immunogen shows no significant sequence homology with mammalian Clock or Per proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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