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You are here:Home » Molecular Biology » Growth Factors-BMP » pro Bone Morphogenetic Protein 2 (pro BMP2), Human, Recombinant

pro Bone Morphogenetic Protein 2 (pro BMP2), Human, Recombinant

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Specifications

proBMP-2 is the pro-protein of BMP-2 and processed by proteases into mature BMP-2. The role of the pro-sequence that exceeds in length (263 amino acids) the mature part (114 amino acids) is currently not known. The rh proBMP-2 correponds to the authentic natural
protein with 377 amino acids.
Catalog #B2553-06C
Rh proBMP-2 is recombinantly expressed in Escherichia coli, native protein is obtained upon refolding of inclusion body material.
Molecular mass 85.476kD
Biological ActivityRecombinant, Human proBMP-2 administration leads to ectopic bone formation ion rats (Hillger et al., 2005).
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 20mM AcOH with 0.1% HSA or BSA and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight26018D
SourceRecombinant, Human (E. coli).
Purity98% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
Concentration~1mg/ml
FormSupplied as a lyophilized powder in a filtered buffer solution.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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