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Bone Morphogenetic Protein 2, 283-396aa, Recombinant, Human (BMP2)
Bone Morphogenetic Protein 2, 283-396aa, Recombinant, Human (BMP2)
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| BMP-2 (Bone morphogenetic protein 2) is multi-functional growth factors that belong to the transforming growth factor beta (TGF beta) superfamily. It plays an important role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility. Recombinant human BMP-2 protein was expressed in E. coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer. | | | Catalog # | B2553-08A | | Endotoxin Level | 1.0 EU per 1 ug of protein (determined by LAL method)15% SDS-PAGE (3ug) | | Molecular Weight | 13kD (115aa) | | AA Sequence | MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM | | LYLDENEKVV LKNYQDMVVE GCGCR | | Storage and Stability | For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 13kD | | Source | E. coli | | Purity | 95% by SDS-PAGE | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 10 mM Sodium Citrate, pH 3.5, 10% glycerol. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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