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You are here:Home » Growth Factors, Cytokines » Growth Factors-BMP » Bone Morphogenetic Protein 2, Recombinant, Human (BMP-2) (Human Cells)

Bone Morphogenetic Protein 2, Recombinant, Human (BMP-2) (Human Cells)

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Specifications

BMP-2 belongs to the bone morphogenetic protein family, a subgroup of the TGF-beta superfamily. BMP-2 is important during embryogenesis especially for skeletal developement and induces chondrocytes formation and osteoblast differentation. BMPs are involved in dorsal-ventral patterning of the embryo and organogenesis.
Catalog #B2553-08B
ActivityThe specific activity was determined by its ability to induce alkaline phosphatase production in a dose response to BMP-2 in the ATDC-5 cell line (Mouse chondrogenic cell line).
Specific Activity~20-100ng/ml ED50
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 4mM HC, 0.1% endotoxin-free recombinant HSA. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight30-38kD
Recombinant protein corresponding to Human BMP-2 expressed in engineered human cells as a glycosylated dimer with an apparent molecular mass of 30-38kD.
Purity95% as determined by SDS-PAGE and stained with Coomassie blue
FormSupplied as a lyophilized powder from PBS. Reconstitute with sterile 4mM HCl, 0.1% endotoxin-free recombinant HSA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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