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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -Bone Morphogenetic Protein 7 (BMP7, OP-1, Osteogenic Protein-1)

Anti -Bone Morphogenetic Protein 7 (BMP7, OP-1, Osteogenic Protein-1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
BMP-7 (bone morphogenetic protein-7), also known as OP-1 (osteogenic protein-1), is a member of the transforming growth factor b(TGF beta) superfamily. BMP-7 plays an essential role during ontogeny of the mammalian eye and kidney, also, is expressed in heart, lung, small intestine, limb bud and teeth. In addition, noggin, one of the soluble BMP antagonists, regulated the action of BMPs on mesenchymal precursor cells, partially through a feedback type of inhibition.
Catalog #B2553-33G
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA(Direct, Sandwich): 0.5-2ug/ml use 100ul/well. In conjunction with compatible secondary reagents, allows the detection of 0.2-0.4ng/well of recombinant hBMP-7.
Western Blot: 0.1-0.2ug/ml. Used in conjunction with compatible secondary reagents the detection limit is 1.5-3.0ng/lane, under either reducing or non-reducing conditions.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH7.2.
PurityPurified by immunoaffinity chromatography.
ImmunogenHighly pure (> 98%) recombinant human BMP-7.
SpecificityRecognizes human BMP-7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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