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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -Bone Morphogenetic Protein 10 (BMP10)

Anti -Bone Morphogenetic Protein 10 (BMP10)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IH
Bone morphogenetic protein 10 (BMP-10) is a TGF-b superfamily member whose expression is restricted to the developing and postnatal heart. It is synthesized as a 424aa pre-proprotein with a putative 21aa signal peptide, a 292aa propeptide, and a 108aa mature protein. Mature BMP-10 is secreted as a 25kD disulfide-linked homodimer. The mouse BMP-10 proprotein shares 86-95aa sequence identity with human and rat BMP-10, respectively.
Catalog #B2553-37J
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 8-25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No11n14
HostRat
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant corresponding to aa314-421 from human BMP-10 expressed in CHO cells (Q9R229).
SpecificityRecognizes mouse BMP-10. Species sequence homology: recombinant human BMP-10, rhBMP-8a (10%), recombinant mouse BMP-8b. Does not react with rmBMP-3, -4, -5, -6, -7, -9, -15, rhBMP-1.1, -2, -3b, propeptide rhBMP-10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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