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You are here:Home » Antibodies » Abs to Receptors, Growth Factor » Anti -BMPR1A (Bone Morphogenetic Protein Receptor Type-1A, BMP Type-1A Receptor, BMPR-1A, Serine/Threonine-protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3, CD292, ACVRLK3, ALK3)

Anti -BMPR1A (Bone Morphogenetic Protein Receptor Type-1A, BMP Type-1A Receptor, BMPR-1A,
Serine/Threonine-protein Kinase Receptor R5, SKR5, Activin Receptor-like Kinase 3, ALK-3,
CD292, ACVRLK3, ALK3)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55kD and type II receptors of about 70-80kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Catalog #B2553-62B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1-5ug/ml using the recombinant protein.
Western Blot (Transfected lysate): 0.1-5ug/ml. Specific band detected at ~60kD using BMPR1A transfected 293T lysate.
Western Blot (Recombinant protein): 1-5ug/ml. Specific band detected at ~85kD using immunogen protein lysate.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a, k
Clone No4C4
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified
ImmunogenRecombinant corresponding to aa1-533 of full length of human BMPR1A with GST tag (AAH28383). MW of the GST tag: 26kD.
SpecificityRecognizes human BMPR1A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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