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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -BORG2 (Binder of Rho GTPases 2, CDC42 Effector Protein (Rho GTPase Binding) 3, Cdc42 Effector Protein 3, CDC42EP3, CEP3, ORG2, UB1)

Anti -BORG2 (Binder of Rho GTPases 2, CDC42 Effector Protein (Rho GTPase Binding) 3, Cdc42
Effector Protein 3, CDC42EP3, CEP3, ORG2, UB1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IP
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation.
Catalog #B2554-15A
ApplicationsSuitable for use in Immunoprecipitation. Not recommended for Western Blot. Other applications not tested.
Recommended DilutionImmunoprecipitation: 2-5ug/mg lysate
Optimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized by this antibody maps to a region between residue 204 and 254 of human binder of Rho GTPases 2 using the numbering given in entry NP_006440.2
SpecificitySpecies Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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