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8-Br-cAMP (8-Bromoadenosine-3', 5'-cyclic Monophosphate, Cyclic 8-bromoadenosine-3', 5'-monophosphate; 8-bromoadenosine-3', 5'-Monophosphate)
8-Br-cAMP (8-Bromoadenosine-3', 5'-cyclic Monophosphate, Cyclic 8-bromoadenosine-3', 5'-monophosphate; 8-bromoadenosine-3', 5'-Monophosphate)
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| A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. Also recently shown to improve the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells 2-fold. | | | Catalog # | B2671-10 | | Solubility | H2O (~100mg/ml) | | Molecular Weight | ~430.08 | | CAS Number | 76939-46-3 | | Molecular Formula | C H BrN O P. Na | | Molecular Weight | ~430.08 | | Purity | ~98% (TLC) | | Concentration | Not determined | | Form | Supplied as a solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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