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You are here:Home » Antibodies » Abs to Peptides » Anti -Brain Natriuretic Peptide, Pro, NT, aa13-27 (NT-proBNP, N-terminal prohormone brain natriuretic peptide)

Anti -Brain Natriuretic Peptide, Pro, NT, aa13-27 (NT-proBNP, N-terminal prohormone brain
natriuretic peptide)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134aa precursor (prepro-BNP), which is cleaved by proteases to form a 26aa "signal" peptide and a 108aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76aa amino-terminal NT-proBNP and biologically active 32aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
Catalog #B2702-01C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Matched PairsCapture: B2702-04T
Detection: B2702-01C
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9L425
HostMouse
SourceHuman
Concentration~7mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa13-27 of the proBNP sequence.
SpecificityRecognizes human proBNP and NT-proBNP (recombinant and synthetic) (aa13-27).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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