You are here:Home
»
Molecular Biology
»
MB-Peptides
»
Brain Natriuretic Peptide, Pro, NT, aa1-76 (NT-proBNP, N-terminal prohormone brain natriuretic peptide)
Brain Natriuretic Peptide, Pro, NT, aa1-76 (NT-proBNP, N-terminal prohormone brain
natriuretic peptide)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. | | | Catalog # | B2702-03D | | BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. | | Applications | Specific methodologies have not been tested using this product. Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 0.1% acetic acid and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Source | Synthetic | | Purity | 95% (HPLC) | | Concentration | Not determined | | Form | Supplied as a lyophilized powder. Reconstitute in 0.1% acetic acid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
