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Anti -Brain Natriuretic Peptide, Pro, NT (BNP)
Anti -Brain Natriuretic Peptide, Pro, NT (BNP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E IH |
|
| Brain-type Natriuretic Peptide (BNP) is a nonglycosylated peptide that is produced predominantly by ventricular myocytes and belongs to the natriuretic peptide family. Proteolytic cleavage of the 12kD BNP precursor gives rise to N-terminal proBNP (NT-proBNP) and mature BNP. Plasma NT-proBNP is a marker for congestive heart failure, while mature BNP (aa103-134) promotes vasodilation and fluid and sodium excretion. | | | Catalog # | B2702-04W | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Direct ELISA: 0.5-1ug/ml. The detection limit is ~20ng/well for recombinant human BNP. | | Immunohistochemistry: 25ug/ml detects proBNP in paraffin-embedded normal human heart tissue sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 8H160 | | Host | Rat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | E. coli-derived recombinant human proBNP (aa27-134, Accession #P16860). Species Sequence Homology: porcine (51%), mouse (29%). | | Specificity | Recognizes human proBNP. Does not react with BNP-32 (aa103-134). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | BNP Precursor |
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