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You are here:Home » Antibodies » Abs to Peptides » Anti -Brain Natriuretic Peptide (BNP)

Anti -Brain Natriuretic Peptide (BNP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH
Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation.
Catalog #B2702-05A
BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure.
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Frozen): 1:2000-1:8000 Staining of BNP in tissue sections is abolished in the presence of 100nmol BNP. There is no inhibition of staining with ANP.
Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies I1903-30U IgG, H&L, X-adsorbed (HRP) ShxRb
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a liquid in 0.09% sodium azide.
PuritySerum
SpecificityRecognizes rat brain natriuretic peptide. Staining of BNP in tissue sections is abolished in the presence of 100nmol BNP. There is no inhibition of staining with ANP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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