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You are here:Home » Antibodies » Abs to Peptides » Anti -Brain Natriuretic Peptide (BNP)

Anti -Brain Natriuretic Peptide (BNP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit E
Brain natriuretic peptide-BNP 32 (also known as B-type natriuretic peptide or "GC-B") is a 32-amino-acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of myocytes (heart muscles cells) in the ventricles. At the time of release, a co-secreted 76 amino acid n-terminal fragment (NT-proBNP) is also released with B-type natriuretic peptide BNP. B-type natriuretic peptide BNP binds to and activates NPRA in a similar fashion to atrial natriuretic peptide but with 10-fold lower affinity. The biological half-life of BNP however, is twice as long as that of ANP. Both ANP and B-type natriuretic peptide BNP have limited ability to bind and activate NPRB.
Catalog #B2702-29C
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS pH 7.2.
ImmunogenHuman BNP.
SpecificityRecognizes human BNP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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