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You are here:Home » Antibodies » Abs to Peptides » Anti -Brain Natriuretic Peptide (BNP)

Anti -Brain Natriuretic Peptide (BNP)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation.
Catalog #B2702-29G
BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure.
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Matched PairSuitable for use as the capture or solid phase antibody.
Matched to B2702-29F, B2702-29H as the detection or conjugate (label) antibody.
Capture: B2702-29G
HybridomaDerived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No5E514
HostMouse
SourceHuman
Concentration~2mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic BNP (whole molecule), conjugated with carrier protein
SpecificityRecognizes human BNP and proBNP. Also recognizes synthetic peptide 26CKVLRRH32.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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