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Anti -Brain Natriuretic Peptide, aa1-21 (BNP)
Anti -Brain Natriuretic Peptide, aa1-21 (BNP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E |
|
| Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. | | | Catalog # | B2702-34D | | BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 32-6-7 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder in 200mM Na Citrate-Tris, 500mM sodium chloride, pH 7.5, 0.02% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Synthetic human pro-BNP (aa 1-21) polylysinee conjugated (HPLGSPGSASDLETSGLQEQR) | | Specificity | Recognizes synthetic human pro-Brain Natriuretic Peptide (aa 1-21) | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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