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Anti -Brain Natriuretic Peptide, aa32-57 (BNP)
Anti -Brain Natriuretic Peptide, aa32-57 (BNP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Serum |
E |
|
| Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesized as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. | | | Catalog # | B2702-35 | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: capture antibody | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 20ul sterile ddH2O. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to aa32-57, QVEQTSLEPLQESPRPTGVWKSREVA of human pro-BNP. | | | Specificity | Recognizes synthetic human pro-Brain Natriuretic Peptide (aa32-57). Does not crossreact with human pro-BNP (aa8-29). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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