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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -BRCA1 (Breast Cancer 1, Early Onset, Breast-Ovarian Cancer Susceptibility)

Anti -BRCA1 (Breast Cancer 1, Early Onset, Breast-Ovarian Cancer Susceptibility)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The novel BRCA1 proteinís epitope, SSKKQKRSHK, was mapped to the cytoplasm of MCF-7 cells. munohistochemistry analysis showed that the antigen epitope exhibited positive expression in 65% of breast cancer specimens. Its expression is associated with characteristics that are associated with prognosis of breast cancer, and its sera antibody level may be helpful for breast cancer diagnosis.
Catalog #B2709-04
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide aa1046-1055 (SSKKQKRSHK]) of the human 136kD BRCA1 protein.
SpecificityRecognizes human residues 1046-1055 (SSKKQKRSHK) of the 136kD BRCA1 protein. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAT rich interactive domain 4B (RBP1- like) isoform 1; RBP1-like protein; breast carcinoma-associated antigen BCAA; breast cancer-associated antigen BRCAA1; Rb-binding protein homolog; retinoblastoma-binding protein 1-like 1; SIN3A-associated protein 180


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