You are here:Home
»
Antibodies
»
Abs to Cancer Markers
»
Anti -BRCA1 (Breast Cancer 1, Early Onset, Breast-Ovarian Cancer Susceptibility)
Anti -BRCA1 (Breast Cancer 1, Early Onset, Breast-Ovarian Cancer Susceptibility)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| The novel BRCA1 protein’s epitope, SSKKQKRSHK, was mapped to the cytoplasm of MCF-7 cells. munohistochemistry analysis showed that the antigen epitope exhibited positive expression in 65% of breast cancer specimens. Its expression is associated with characteristics that are associated with prognosis of breast cancer, and its sera antibody level may be helpful for breast cancer diagnosis. | | | Catalog # | B2709-04 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:1000. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide aa1046-1055 (SSKKQKRSHK]) of the human 136kD BRCA1 protein. | | Specificity | Recognizes human residues 1046-1055 (SSKKQKRSHK) of the 136kD BRCA1 protein. Species Crossreactivity: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | AT rich interactive domain 4B (RBP1- like) isoform 1; RBP1-like protein; breast carcinoma-associated antigen BCAA; breast cancer-associated antigen BRCAA1; Rb-binding protein homolog; retinoblastoma-binding protein 1-like 1; SIN3A-associated protein 180 |
External Links
|
