Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -BRCA1 (Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Cancer Type 1 Susceptibility Protein, BRCC1, Breast Ovarian Cancer Susceptibility, Papillary Serous Carcinoma of the Peritoneum, PSCP, RING Finger Protein 53, RNF53)

Anti -BRCA1 (Breast Cancer 1, Breast Cancer 1 Early Onset, Breast Cancer Type 1
Susceptibility Protein, BRCC1, Breast Ovarian Cancer Susceptibility, Papillary Serous
Carcinoma of the Peritoneum, PSCP, RING Finger Protein 53, RNF53)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
The interaction between BRCA1 and BARD1 (BRCA1 associated RING domain 1) through an amino-terminal RING finger domain, is implicated in RNA processing following DNA damage, and also in the mediation of tumor suppression by BRCA1. Gene mutations in BRCA1 are known to greatly enhance susceptibility to inherited breast, breast-ovarian and prostate cancers, and BRCA1 is therefore commonly used as a diagnostic marker for breast cancer.
Catalog #B2709-06A
ApplicationsSuitable for use in Immunoprecipitation and Western Blot. Other applications not tested.
Recommended DilutionImmunoprecipitation: 1-4ug/mg
Western Blot: 1:1,000-1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in tris-citrate/phosphate, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to an epitope within aa residues 1800-1863 of human BRCA1 (NP_009225.1).
SpecificityRecognizes human BRCA1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesBRAC1, IRIS


External Links