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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Breast Cancer Resistance Protein (BCRP)

Anti -Breast Cancer Resistance Protein (BCRP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH IC FC
Breast Cancer Resistance Protein (BCRP) is a 70kD ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.
Catalog #B2738-01A
Applications
Suitable for use in Flow Cytometry, Immunocytochemistry and Immunohistochemistry. Not recommended for Western Blot. Other applications have not been tested.
Recommended DilutionImmunocytochemistry: 1:20-1:50 using acetone-fixed cytospin preparations.
Immunohistochemistry (frozen sections): 1:20 dilution using acetone fixed frozen sections followed by incubation with rabbit anti-mouse IgG and a monoclonal mouse APAAP complex. Not suitable for use on formaldehyde-fixed paraffin-embedded human tissues and tumors.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No6D169
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.7% BSA, % sodium azide.
PuritySupernatant
ImmunogenMitoxanthone resistant BCRP (breast cancer resistance protein; MXR) overexpressing cell line MCF7MR.
SpecificityRecognizes an internal epitope of human BCRP. Does not cross-react with human P-glycoprotein, MRP1, MRP2 or MRP5.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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