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Anti -Breast Cancer Resistance Protein (BCRP)
Anti -Breast Cancer Resistance Protein (BCRP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Supernatant |
B IH IC |
|
| Breast Cancer Resistance Protein (BCRP) is a 70kD ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone. | | | Catalog # | B2738-03 | | Applications | Suitable for use in Immunocytochemistry, Western Blot and Immunohistochemistry and Other applications not tested. | | Recommended Dilution | Immunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations. | | Immunohistochemistry (frozen sections): 1:20 on acetone fixed frozen sections followed by incubation with biotin-labelled rabbit anti-rat IgG and HRP-labelled streptavidin. | | (For paraffin sections see ref 1.) | | Western Blot: 1:20-1:50 dilution using HRP-labelled anti-rat IgG. | | Optimal dilutions to be determined by the researcher. | | | | Storage and Stability: | | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 6D170 | | Host | Rat | | Source | Mouse | | Concentration | Not determined | | Form | Supplied as a liquid, 0.7% BSA and 0.1% sodium azide. | | Purity | Supernatant | | Immunogen | Recombinant mouse BCRP (breast cancer resistance protein; MXR) (aa 221-394). | | Specificity | Recognizes an internal epitope of mouse BCRP. | | Species Crossreactivity | Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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