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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Breast Cancer Resistance Protein (BCRP)

Anti -Breast Cancer Resistance Protein (BCRP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Supernatant B IH IC
Breast Cancer Resistance Protein (BCRP) is a 70kD ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.
Catalog #B2738-03
ApplicationsSuitable for use in Immunocytochemistry, Western Blot and Immunohistochemistry and Other applications not tested.
Recommended DilutionImmunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations.
Immunohistochemistry (frozen sections): 1:20 on acetone fixed frozen sections followed by incubation with biotin-labelled rabbit anti-rat IgG and HRP-labelled streptavidin.
(For paraffin sections see ref 1.)
Western Blot: 1:20-1:50 dilution using HRP-labelled anti-rat IgG.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No6D170
HostRat
SourceMouse
ConcentrationNot determined
FormSupplied as a liquid, 0.7% BSA and 0.1% sodium azide.
PuritySupernatant
ImmunogenRecombinant mouse BCRP (breast cancer resistance protein; MXR) (aa 221-394).
SpecificityRecognizes an internal epitope of mouse BCRP.
Species CrossreactivityHuman.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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