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Anti -Breast Cancer Resistance Protein (BCRP)
Anti -Breast Cancer Resistance Protein (BCRP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
B IH IC |
|
| Breast Cancer Resistance Protein (BCRP) is a 70kD ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone. | | | Catalog # | B2738A | | Applications | | | Suitable for use in Immunocytochemistry, Immunohistochemistry and Western Blot. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Frozen): 1:20 dilution on acetone fixed frozen sections followed by incubation with rabbit anti-mouse IgG and a monoclonal mouse APAAP complex. | | Immunohistochemistry (Paraffin): Use on formaldehyde-fixed paraffin-embedded human tissues and tumors after pretreatment with 10mM citric acid, pH 6.0, for 20 min. | | Immunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 6D171 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.7% BSA, 0.1% sodium azide. | | Purity | Supernatant | | Immunogen | Recombinant protein corresponding to aa271-396 from human Breast Cancer Resistance Protein. | | Specificity | Recognizes an internal epitope of human Breast Cancer Resistance Protein. Does not cross-react with human P-glycoprotein, MRP1 or MRP2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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