You are here:Home
»
Antibodies
»
Abs to Binding Proteins
»
Anti -Brevican (BEHAB, Brain-Enriched Hyaluronan-Binding Protein)
Anti -Brevican (BEHAB, Brain-Enriched Hyaluronan-Binding Protein)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
E B |
|
| Brevican (brain-enriched hyaluronan-binding protein) is a 160kD member of the aggrecan/versican proteoglycan family of matrix proteins. It is brain-derived and serves as a linker between HA and other matrix molecules such as tenascins and fibulins. Mature human Brevican is 889 amino acids in length. It contains multiple domains, with an N-terminal V-type Ig-like domain (aa # 52-139) and a C-terminal EGF-like domain (aa # 646-682) and a C-type lectin domain (aa # 695-802). Multiple isoforms exist where there is an alternate start site at Met228 and a 23 aa substitution for aa # 649-911 that serves as a GPI-anchor motif. Over aa #23-911, human Brevican shares 82% aa identity with mouse Brevican. | | | Catalog # | B2739-70 | | Applications | Suitable for use in Western Blot and ELISA. Other applications not tested. | | Recommended Dilution | Western Blot: 0.1-0.2ug/ml | | ELISA: 0.5-1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol. | | Purity | Purified by human Brevican affinity chromatography. | | Immunogen | NS0-derived recombinant human Brevican isoform 1 (aa23-911) Accession # Q96GW7, Lys504Glu substitution | | Specificity | Recognizes human Brevican. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
