You are here:Home
»
Antibodies
»
Abs to Nucleotides
»
Anti -Bromodeoxyuridine (BrdU)
Anti -Bromodeoxyuridine (BrdU)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
FC |
|
| Bromodeoxyuridine (BrdU) is a thymidine analog and is specifically incorporated into DNA during DNA synthesis. Anti-bromodeoxyuridine monoclonal antibody is used to identify cells that have incorporated BrdU. This immunological detection scheme has several advantages over the use of radioactive thymidine incorporation for identifying cells under-going replication. Labeling and detection can be performed the same day instead of waiting several days, as required for autoradiography of tritium-labeled cells, and the necessity of using multiple specimens for obtaining the optimal exposure time is eliminated. In addition, anti-bromodeoxyuridine staining with flow cytometric analysis allows multiple parameters to be evaluated simultaneously. Anti-bromodeoxyuridine monoclonal antibody has been used for identifying proliferating cells in blood (1), tissues (2,3), tumors (4–7), as well as for determining plasma cell labeling indices (8). | | | Catalog # | B2850-14 | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 2Q2284 | | Host | Mouse | | Concentration | ~1mg/ml | | Form | Liquid in 10mM Phosphate buffer, pH 7.4 containing 150mM sodium chloride and 0.1% sodium azide. | | Purity | Purified immunoglobulin | | Immunogen | Bromodeoxyuridine BSA conjugate | | Specificity | Binds to bromodeoxyuridine and crossreacts with iodouridine (10%). Does not crossreact with fluorodeoxyuridine, nor with any endogenous cellular components such as thymidine or uridine. | | | Important Note | This product is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
External Links
|