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You are here:Home » Molecular Biology » MB-CD Markers » BTLA, Mouse IgG2a Fc Fusion Protein (B- and T-lymphocyte Attenuator, B- and T-lymphocyte-associated Protein, BTLA1, CD272, FLJ16065, MGC129743)

BTLA, Mouse IgG2a Fc Fusion Protein (B- and T-lymphocyte Attenuator, B- and
T-lymphocyte-associated Protein, BTLA1, CD272, FLJ16065, MGC129743)

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Specifications

Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the Immunoglobulin superfamily and has homology to CD152 (CTLA-4). Engagement of BTLA by its co receptor CD270 (HVEM, a TNF superfamily member) can down regulate activated T and B cell responses. BTLA levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines (1).
Catalog #B5001-61N
ReactivityCD272-muIg binds to recombinant HVEM-muIg.
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PurityPurified by size exclusion.
Concentration~0.5mg/ml
FormSupplied as liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 150mM sodium chloride. No preservative added.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesB and T Lymphocyte Associated


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