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BTLA, Mouse IgG2a Fc Fusion Protein (B- and T-lymphocyte Attenuator, B- and T-lymphocyte-associated Protein, BTLA1, CD272, FLJ16065, MGC129743)
BTLA, Mouse IgG2a Fc Fusion Protein (B- and T-lymphocyte Attenuator, B- and
T-lymphocyte-associated Protein, BTLA1, CD272, FLJ16065, MGC129743)
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| Human CD272 (BTLA, B and T Lymphocyte Attenuator) is a member of the Immunoglobulin superfamily and has homology to CD152 (CTLA-4). Engagement of BTLA by its co receptor CD270 (HVEM, a TNF superfamily member) can down regulate activated T and B cell responses. BTLA levels on antigen specific CD8+ T cells have been reported to decrease in viral specific, but not melanoma specific activated lines (1). | | | Catalog # | B5001-61N | | Reactivity | CD272-muIg binds to recombinant HVEM-muIg. | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | Purity | Purified by size exclusion. | | Concentration | ~0.5mg/ml | | Form | Supplied as liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 150mM sodium chloride. No preservative added. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | B and T Lymphocyte Associated |
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