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You are here:Home » Antibodies » Antibodies-Disease Markers » Anti -C-1 Inhibitor (C1-INH)

Anti -C-1 Inhibitor (C1-INH)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of 104kD (1,2). Serum concentration has been determined to 180ug/ml (2).
Catalog #C0002-04
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:16000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No8F3
FormSupplied as a liquid in PBS, pH 7.2, 15mM sodium azide.
PurityPurified by Protein A/G affinity chromatography from culture supernatant.
ImmunogenC1-inhibitor (C1INH) isolated from human plasma.
SpecificitySpecific for human C1-inhibitor (C1-INH). Epitope specificity differs from that of clone 6F42.
Reacts strongly with C1INH. Strong reaction is seen with human serum/plasma when tested in sandwich ELISA in combination with a polyclonal antibody against C1INH, and in ELISA with C1INH coated directly onto the microtiter well.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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