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You are here:Home » Antibodies » Abs to Complement » Anti -Complement C1q (Complement Component 1, q Subcomponent)

Anti -Complement C1q (Complement Component 1, q Subcomponent)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Highly Purified
Human complement component 1, q subcomponent (C1q) is a 156kD secreted protein. C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.
Catalog #C0010-02J
ApplicationsSuitable for use in Immunodiffusion. Other applications not tested.
Recommended DilutionImmunodiffusion: Neat
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostSheep
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid in glycine buffered saline, pH 7.4, 0.09% sodium, 0.1% azide, 0.01% EACA, 1mM Benzamidine EDTA.
PurityPurified by Ion Exchange chromatography.
ImmunogenHuman C1q, purified from plasma.
SpecificityRecognizes human C1q.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesComplement C1q Subcomponent Subunit A, Complement Component 1 q Subcomponent A Chain, C1QA, Complement C1q Subcomponent Subunit B, Complement Component 1 q Subcomponent B Chain, C1QB, Complement C1q Subcomponent Subunit C, Complement Component 1 q Subcomp


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