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C0010-07H Complement C1q, Human CAS:

Specifications
References
Grade
Highly Purified
Molecular Weight
410
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
4°C Do not freeze
Adipocyte Complement-related Protein of 30kD, AdipoQ, APM1, Adiponectin, Gelatin Binding Protein 28kD, GBP28, Adipocyte Most Abundant Gene Transcript

Human C1q produced in Human plasma having a molecular mass of 410kD. The C1 component of complement is a complex of 2 C1q sub-units and a tetramer comprising 2 C1r and 2 C1s sub-units. C1 activation is regulated by an inhibitor (C1 inhibitor). Reductions in the levels of components C3, C4, C1 and C2 can be associated with glomerular disease, endocarditis and systemic lupus erythematosus (SLE).

Storage and Stability
Lyophilized and reconstituted products are stable for 6 months after receipt at 4°C. Reconstitute with sterile ddH2O. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Source
Human plasma
Purity
≥96%
Concentration
As reported
Form
Supplied as a lyophilized powder from 0.01M sodium EDTA, 0.3M sodium chloride, pH 7.5. Reconstitute with sterile ddH2O
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Human complement component C1q inhibits the infectivity of cell-free HTLV-I. J Immunol 1998 Nov 15;161(10):5712-9 2. Collagenase of Clostridium perfringens type A: degradation of human complement component C1q. Zentralbl Bakteriol 1991 Dec;276(1):27-35 3. The binding properties of human complement component C1q. Interaction with mucopolysaccharides. J Biol Chem 1983 Jan 25;258(2):785-91
USBio References
No references available
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