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You are here:Home » Antibodies » Abs to Peptides » Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (Carboxyfluorescein)

Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a
Receptor 1) (Carboxyfluorescein)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
C5a R, also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5a R binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of pro-inflammatory mediators. In contrast, C5a R/C5a interactions are protective during allergen sensitization. Human C5a R shares 66% amino acid sequence identity with mouse and rat C5a R.
Catalog #C0012-01F
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9H73
HostMouse
SourceHuman
Concentration~25ug/ml
FormSupplied as a lyophilized powder in 25ug antibody, 1ml saline, 0.5% BSA, 0.1% sodium azide. Reconstitute with 40-50% glycerol, PBS. Labeled with Carboxyfluorescein.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0 cells transfected with human Complement component 5 receptor 1 NP_001727.
SpecificityRecognizes human Complement component 5 receptor 1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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