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Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (Carboxyfluorescein)
Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a
Receptor 1) (Carboxyfluorescein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| C5a R, also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5a R binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of pro-inflammatory mediators. In contrast, C5a R/C5a interactions are protective during allergen sensitization. Human C5a R shares 66% amino acid sequence identity with mouse and rat C5a R. | | | Catalog # | C0012-01F | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 9H73 | | Host | Mouse | | Source | Human | | Concentration | ~25ug/ml | | Form | Supplied as a lyophilized powder in 25ug antibody, 1ml saline, 0.5% BSA, 0.1% sodium azide. Reconstitute with 40-50% glycerol, PBS. Labeled with Carboxyfluorescein. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | NS0 cells transfected with human Complement component 5 receptor 1 NP_001727. | | Specificity | Recognizes human Complement component 5 receptor 1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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