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You are here:Home » Antibodies » Abs to Complement » Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (APC)

Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a
Receptor 1) (APC)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
C5a R, also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5a R binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of pro-inflammatory mediators. In contrast, C5a R/C5a interactions are protective during allergen sensitization. Human C5a R shares 66% amino acid sequence identity with mouse and rat C5a R.
Catalog #C0012-01G
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9H74
HostMouse
SourceHuman
Concentration~10ug/ml
FormSupplied as a liquid in PBS, 0.5% BSA and 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0 cells transfected with human Complement component 5 receptor 1 NP_001727.
SpecificityRecognizes human Complement component 5 receptor 1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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