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Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a Receptor 1) (APC)
Anti -Complement Component C5a R (CD88, C5a Receptor 1, C5aR1, Complement Component 5a
Receptor 1) (APC)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| C5a R, also known as C5a ligand and CD88, is a 7TM protein expressed on myeloid, endothelial, epithelial, and smooth muscle cells. C5a R binds the activated complement anaphylatoxin C5a. In established allergic environments, this triggers neutrophil and eosinophil chemotaxis and the release of pro-inflammatory mediators. In contrast, C5a R/C5a interactions are protective during allergen sensitization. Human C5a R shares 66% amino acid sequence identity with mouse and rat C5a R. | | | Catalog # | C0012-01G | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 9H74 | | Host | Mouse | | Source | Human | | Concentration | ~10ug/ml | | Form | Supplied as a liquid in PBS, 0.5% BSA and 0.1% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | NS0 cells transfected with human Complement component 5 receptor 1 NP_001727. | | Specificity | Recognizes human Complement component 5 receptor 1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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